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{"id":721285,"type":0,"block_id":"cjgeist_1362688124","theme_id":20,"user_id":250142,"path":"Hodgkin-355723463","title":"Hodgkin&#39;s Lymphoma","pubtitle":"Hodgkin&#39;s Lymphoma","tags":"","public":true,"publicAccess":true,"private_link_enabled":0,"thumb":"https://s3-eu-west-1.amazonaws.com/infogram-thumbs-200/cjgeist_1362688124.jpg","width":550,"copyright":null,"properties":{"transparent":false,"rtl":false,"export_settings":{"showGrid":true,"showValues":true},"whitelabel":false,"embed_button":"enabled","title_link":"infogram","custom_logo":"infogram","custom_link_url":"","embed_button_text":"Share","decimal_separator":".,"},"elements":[{"type":"particle","particle_id":13466110,"object_id":"730d6c86-ea3f-11e4-a037-7b5f270fdca9","particle_type":"maintitle","picture":null,"text":"Hodgkin&#39;s Lymphoma","content_type":"","title":null,"shrink":null},{"type":"particle","particle_id":701412,"object_id":"cjgeist1363271897","particle_type":"bodytitle","picture":null,"text":"BACKGROUND:","content_type":"","title":"","shrink":null},{"type":"particle","particle_id":697737,"object_id":"cjgeist1362689414","particle_type":"bodytext","picture":null,"text":"Hodgkin&#39;s is a type of lymphoma, a cancer of the lymphatic system. Cells in the lymphatic system can grow abnormally and might spread past the lymphatic system. Hodgkin&#39;s compromises your body&#39;s immune system. Subtypes of Classical Hodgkin&#39;s (the most common type) include, Nodular Sclerosis, Mixed Cellularity, Lymphocyte-depleted, and Lymphocyte-rich classical Hodgkin&#39;s Lymphoma. People with Classical Hodgkins have large, abnormal cells (Reed Sternberg cells) in their lymph nodes. Lymphocyte-predominant Hodgkin&#39;s lymphoma (rare type) has large, abnormal cells that can be referred to as popcorn cells because of their appearance.","content_type":"","title":"","shrink":null},{"type":"particle","particle_id":725566,"object_id":"cjgeist1363199152","particle_type":"image","picture":"http://s3-eu-west-1.amazonaws.com/infogram-particles-700/cjgeist1363199152.jpg"},{"type":"particle","particle_id":729939,"object_id":"cjgeist1363273994","particle_type":"bodytitle","picture":null,"text":"SYMPTOMS:","content_type":"","title":"","shrink":null},{"type":"particle","particle_id":697707,"object_id":"cjgeist1362688208","particle_type":"bodytext","picture":null,"text":"~Swelling of lymph nodes in neck, armpits, groin\n~Fatigue\n~Fever and chills\n~Night sweats\n~Unexplained weight lost\n~Coughing, trouble breathing or chest pain\n~Loss of Appetite\n~Itching","content_type":"","title":"","shrink":null},{"type":"particle","particle_id":720509,"object_id":"cjgeist1363274059","particle_type":"bodytitle","picture":null,"text":"GENETICS:","content_type":"","title":"","shrink":null},{"type":"particle","particle_id":619232,"object_id":"cjgeist1362689155","particle_type":"bodytext","picture":null,"text":"Hodgkin&#39;s mostly occurs when a B cell (infection fighting cell) has a mutation in its DNA. HRS and L&H cells show mutated immunoglobulin genes, these cells are called a germinal center B cells. These cells can show further mutations of the oncogenes and tumor suppressor genes such as, p53 or CD95/Fas.","content_type":"","title":"","shrink":null},{"type":"particle","particle_id":725589,"object_id":"cjgeist1363199158","particle_type":"image","picture":"http://s3-eu-west-1.amazonaws.com/infogram-particles-700/cjgeist1363199158.gif"},{"type":"particle","particle_id":697861,"object_id":"cjgeist1362689478","particle_type":"bodytext","picture":null,"text":"Males are more likely to get it. Most people are diagnosed at age 15-35 and 55 and older. If a brother or sister has Hodgkin&#39;s or Non-Hodgkin&#39;s there is an increased risk for developing Hodgkin&#39;s. Hodgkin&#39;s is less than one percent of all cancers. ","content_type":"","title":"","shrink":null},{"type":"particle","particle_id":720499,"object_id":"cjgeist1363274115","particle_type":"bodytitle","picture":null,"text":"STATISTICS:","content_type":"","title":"","shrink":null},{"type":"particle","particle_id":713370,"object_id":"cjgeist1363029338","particle_type":"bodytext","picture":null,"text":"Diagnosis:\n~Biopsy of the lymph node/bone marrow/suspected tissue\nIf tests show you have Hodgkin&#39;s more tests need to be done to determine if it has spread (staging). \n~Blood chemistry tests to determine protein levels, liver function tests, kidney function tests, and uric acid level\n~Bone marrow biopsy\n~CT scans of chest. abdomen, and pelvis\n~Complete blood count (check for anemia and white blood count)\n~PET scan (positron emission tomography)- imaging test that uses radioactive substance, tracer, to search for disease the the body.","content_type":"","title":"","shrink":null},{"type":"chart","chart_id":1129258,"object_id":"cjgeist_1363198551","chart_type_nr":19,"data":[[["","5 year survival rate"],["Stage 1","About 90"],["Stage 2","About 90"],["Stage 3","About 80"],["Stage 4","About 65"]]],"custom":{"showColHeader":true,"pictoProportionalScale":false,"styleName":false},"colors":["#35b099"],"dimensions":[],"modifier":0,"sheetnames":[],"sheets_settings":[]},{"type":"particle","particle_id":729825,"object_id":"cjgeist1363274105","particle_type":"bodytitle","picture":null,"text":"TREATMENTS","content_type":"","title":"","shrink":null},{"type":"particle","particle_id":713312,"object_id":"cjgeist1363028686","particle_type":"bodytext","picture":null,"text":"Treatments that help with other symptoms:\n~Transfusion of platelets or red blood cells to fight low platelet counts and anemia\n~Antibiotics to fight infection\n~Vaccination for against bacteria- pneumococcus, meningococci, and Haemophilus influenzae; these bacteria can cause pneumonia, meningitis, and acute respiratory infections.\n","content_type":"","title":"","shrink":null},{"type":"particle","particle_id":697888,"object_id":"cjgeist1362689641","particle_type":"bodytext","picture":null,"text":"Method of treatment depends on type of Hodgkin&#39;s Lymphoma, the stage, size of tumor, your age and medical issues, and weight loss, night sweats, and fever. Staging will be done (tests to see spread of cancer) to determine treatment plan. \nStages 1 and 2: Radiation and/or chemotherapy\nStage 3: Only chemotherapy or both radiation and chemo.\nStage 4: Chemotherapy alone\nIf lymphoma comes back after treatment is concluded or does not respond to treatment, the patient may undergo high-dose chemotherapy followed by autologous stem cell transplant (using stem cells from yourself).","content_type":"","title":"","shrink":null},{"type":"particle","particle_id":720399,"object_id":"cjgeist1363274282","particle_type":"bodytitle","picture":null,"text":"CAUSES AND RISK FACTORS","content_type":"","title":"","shrink":null},{"type":"particle","particle_id":713429,"object_id":"cjgeist1363029800","particle_type":"bodytext","picture":null,"text":"~Once having mononucleosis (mono), caused by Epstein-Barr virus, increases your risk for Hodgkin&#39;s lymphoma. Only about half of patients with Hodgkin&#39;s have DNA of the virus in the mutated cells.\n~Occurs more often in males.\n~HIV increases risk\n","content_type":"","title":"","shrink":null},{"type":"particle","particle_id":720402,"object_id":"cjgeist1363274414","particle_type":"bodytitle","picture":null,"text":"ANECDOTAL COMPONENT:","content_type":"","title":"","shrink":null},{"type":"particle","particle_id":713587,"object_id":"cjgeist1363031169","particle_type":"bodytext","picture":null,"text":"Melody, a 29 year old women from Canada, one summer came down with mono. Three years later she began having a cough that would come and go. She saw the doctor and was given antibiotics. She got pregnant and the cough came back, but it was even more persistent. She also began developing a rash and was becoming easily fatigued. She went to the doctor and had blood work down. The results showed anemia. After Melody gave birth to her child, the fatigue and cough grew increasingly worse. The cough seemed to come and go on a regular basis. One day she felt a lump on her neck and went to the clinic to get it looked at. The doctor diagnosed her with Hodgkins Lymphoma Nodular Sclerosis. Her lungs would begin to fill with fluid. She would have to get chemotherapy for six months, be home on oxygen 24/7, get her lungs drained every 3 weeks. Then one of Melody&#39;s lungs collapsed and went in for a chest tube procedure. She finished her treatment then relapsed shortly after. Then she started a new treatment plan that consisted of chemo 6 days a week for three weeks for 2-3 months. Then she underwent a stem cell transplant and a bone marrow surgery. Melody is now in remission.","content_type":"","title":"","shrink":null}],"theme":{"createdAt":"2016-04-22T04:54:06.000Z","updatedAt":"2016-12-28T10:32:12.000Z","logoImages":[""],"charts":{"wordcloud":{"labels":{"fontWeight":"700","fontFamily":"Arial"}},"treemap":{"labels":{"value":{"fontFamily":"PT Sans Narrow"},"name":{"fontWeight":"700","fontFamily":"PT Sans Narrow"}}},"table":{"cellBackground":"#ffffff","headerBackground":"#fff","cellColor":"#3e372b","headerColor":"#3e372b","shapeFill":"35b099"}},"color":{"bg":"#ffffff","text":"#000000","chart":{"bg":"transparent","text":"#000000"},"element":{"bg":"transparent","text":"#000000"}},"colorPresets":[],"localFonts":[],"font":{"common":{"fontFamily":"PT Sans","fontWeight":"400","fontStyle":"normal","fontSize":"16","textAlign":"initial"},"legend":{"fontSize":"16","fontWeight":"400"},"label":{"fontSize":16,"fontWeight":400}},"fontPresets":[],"fontFamilies":["Open Sans Condensed","Verdana","PT Sans","PT Sans 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